A looming medical crisis?
Resistance to antibiotics could herald 'end of modern medicine': WHO
Mar 17, 2012
COPENHAGEN - The world is entering an antibiotic crisis which could make routine operations impossible and a scratched knee potentially fatal, the head of the World Health Organization (WHO) has claimed.
WHO director-general Margaret Chan warned that humans have become so resistant to common antibiotics that it could bring about "the end of modern medicine as we know it".
As a result, she claimed, every antibiotic ever developed is at risk of becoming useless, making once-routine operations impossible.
This would include many of the breakthrough drugs developed to treat tuberculosis, malaria, bacterial infections and HIV/AIDS, as well as simple treatments for cuts.
Speaking to a conference of infectious disease experts in Copenhagen, Dr Chan said we could be entering into a "post-antibiotic era". Replacement medicines could become more expensive, with longer periods of treatment required to bring about the same effect, she added.
"Things as common as strep throat or a child's scratched knee could once again kill," said Dr Chan, who handled Hong Kong's 2003 SARS outbreak as the territory's director of health.
"Antimicrobial resistance is on the rise in Europe and elsewhere in the world. We are losing our first-line antimicrobials. Replacement treatments are more costly, more toxic, need much longer durations of treatment, and may require treatment in intensive care units.
"For patients infected with some drug-resistant pathogens, mortality has been shown to increase by around 50 per cent. A post-antibiotic era means, in effect, an end to modern medicine as we know it."
The stark warning comes shortly after the WHO published a new book warning of the "global crisis", entitled The evolving threat of antimicrobial resistance.
The book says that bacteria which cause disease react to the antibiotics used as treatment by becoming resistant to them, sooner or later.
"A crisis has been building up over the decades, so that today many common and life-threatening infections are becoming difficult or even impossible to treat, sometimes turning a common infection into a life-threatening one," it says.
It blamed the current situation largely on the misuse of antibiotics, which are not prescribed properly and used too frequently and for too long, adding that an "inexorable increase in antimicrobial-resistant infections, a dearth of new antibiotics in the pipeline and little incentive for industry to invest in research and development" had led to a need for innovation".
The WHO has now appealed to governments across the world to support research into the antimicrobial resistance.
WHO director-general Margaret Chan warned that humans have become so resistant to common antibiotics that it could bring about "the end of modern medicine as we know it".
As a result, she claimed, every antibiotic ever developed is at risk of becoming useless, making once-routine operations impossible.
This would include many of the breakthrough drugs developed to treat tuberculosis, malaria, bacterial infections and HIV/AIDS, as well as simple treatments for cuts.
Speaking to a conference of infectious disease experts in Copenhagen, Dr Chan said we could be entering into a "post-antibiotic era". Replacement medicines could become more expensive, with longer periods of treatment required to bring about the same effect, she added.
"Things as common as strep throat or a child's scratched knee could once again kill," said Dr Chan, who handled Hong Kong's 2003 SARS outbreak as the territory's director of health.
"Antimicrobial resistance is on the rise in Europe and elsewhere in the world. We are losing our first-line antimicrobials. Replacement treatments are more costly, more toxic, need much longer durations of treatment, and may require treatment in intensive care units.
"For patients infected with some drug-resistant pathogens, mortality has been shown to increase by around 50 per cent. A post-antibiotic era means, in effect, an end to modern medicine as we know it."
The stark warning comes shortly after the WHO published a new book warning of the "global crisis", entitled The evolving threat of antimicrobial resistance.
The book says that bacteria which cause disease react to the antibiotics used as treatment by becoming resistant to them, sooner or later.
"A crisis has been building up over the decades, so that today many common and life-threatening infections are becoming difficult or even impossible to treat, sometimes turning a common infection into a life-threatening one," it says.
It blamed the current situation largely on the misuse of antibiotics, which are not prescribed properly and used too frequently and for too long, adding that an "inexorable increase in antimicrobial-resistant infections, a dearth of new antibiotics in the pipeline and little incentive for industry to invest in research and development" had led to a need for innovation".
The WHO has now appealed to governments across the world to support research into the antimicrobial resistance.
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